Hey there! These canons will, for now, be separated into their different universes (MCU vs XMCU vs 616, DCEU vs DC Animated vs Arrowverse). That said, if one franchise begins to be overrepresented in game, we may come back to this rule and adjust as necessary. As for Preacher, it appears the comics and television series deviate in much the same way the MCU deviates from Marvel 616, in which case yes, they would be separate. If this is inaccurate, please let us know!